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Thus a deficiency in leptin signaling, either via leptin deficiency or leptin resistance, leads to overfeeding and may account for some genetic and acquired forms of obesity.
The Obesity Policy Action OPA framework divides measure into 'upstream' policies, 'midstream' policies, 'downstream' policies.
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This is a comprehensive evidence-based guideline to address the management and prevention of overweight and obesity in adults and children.
In particular, they and other appetite-related hormones act on the hypothalamusa region of the brain central to the regulation of food intake and energy expenditure. As ofmore than 41 of these sites on the human genome have been linked to the development of obesity when a favorable environment is present.
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